Disorders Associated with Lymphatic Vessels

Please go to Evolve Elsevier –go to your Anatomy and Physiology bookàStudents Resources àChapter 19 à Mechanism of diseases,

Summarize briefly these topics and provide a short definition of the following subsequent important medical term or diseases.

I-Disorders Associated with Lymphatic Vessels

  1. Lymphedema
  2. Elephantiasis
  3. Lymphangitis,
  4. Necrosis
  5. Abscesses
  6. Septicemia

II-Disorders Associated with Lymph Nodes and Other Lymphatic Organs

III-Lymphoma Definition and difference between:

  1. Hodgkin lymphoma (HL) and
  2. Non-Hodgkin lymphoma (NHL

IV-Hypersensitivity of the Immune system

  1. Hypersensitivity Allergy
  2. Allergens
  3. Urticaria
  4. Anaphylactic shock.
  5. Antihistamines
  6. Contact dermatitis,
  7. Hypoallergenic


Autoimmune diseases Definition and 3 examples


  1. Isoimmunity
  2. erythroblastosis fetalis.
  3. Graves disease
  4. Myasthenia gravis.
  5. Tissue or organ transplants
  6. Rejection syndrome
  7. Human leukocyte antigens (HLAs)

VII-Difference Host-versus-graft rejection vs Graft-versus-host rejection

VIII-Immune deficiency

  1. Severe combined immune deficiency (SCID)
  2. Acquired immune deficiency syndrome (AIDS).
  3. Human immunodeficiency virus (HIV).
  4. Pneumocystis jiroveci pneumoniae 
  5. Kaposi sarcoma
  6. Highly active antiretroviral therapy (HAART).

IX-Immunity and Cancer

Tumor-specific antigens- Definition

Tumor markers definition and the association to type of cancers

(1) Carcinoibryonic antigen (CEA)

 (2) Alpha-fetoprotein (AFP

 (3) CA-125

 (4) Prostate-specific antigen (PSA)

X-Complete the table of Examples of Autoimmune Diseases

Addison diseaseSurface antigens on adrenal cells             
Cardiomyopathy Disease of cardiac muscle (i.e., the myocardium), resulting in loss of pumping efficiency (heart failure)
Diabetes mellitus (type 1)Pancreatic islet cells, insulin, insulin receptors             
Glomerulonephritis                 Disease of the filtration apparatus of the kidney (renal corpuscle), resulting in fluid and electrolyte imbalance and possibly total kidney failure and death
Graves disease (type of hyperthyroidism)TSH receptors on thyroid cells               
Hemolytic anemia             Condition of low RBC count in the blood resulting from excessive destruction of mature RBCs (hemolysis)
HypothyroidismAntigens in thyroid cells               
Multiple sclerosis (MS)             Progressive degeneration of myelin sheaths, resulting in widespread impairment of nerve function (especially muscle control)
Myasthenia gravisAntigens at neuromuscular junction             
Pernicious anemiaAntigens on parietal cells, intrinsic factor           
Reproductive infertility         Inability to produce offspring (in this case, resulting from destruction of gametes)
Rheumatic fever             Rheumatic heart disease; inflammatory cardiac damage (especially to the endocardium/valves)
Rheumatoid arthritis (RA)Collagen       
Systemic lupus erythematous (SLE)Numerous           
Ulcerative colitis           Chronic inflammatory disease of the colon characterized by watery diarrhea containing blood, mucus, and pus
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